Tag Archives: neuropsychology

What are they high!?!

Jan 2008 30 – Filed under science

A lot of science geeks enjoy lambasting the press for their excessive use of hype in reporting science and medical news. The excellent Bad Science blog specializes in this sort of media skewering, as do several ScienceBlogs writers and other science bloggers.

One problem with all this finger pointing is the fact that scientists and doctors often infuse quite a bit of hyperbole themselves whenever they discuss their research. The discussion section of any paper is often where the forest of wild tangents lives. This is especially true with basic science research where they use this section to say “See! See! Our research is relevant too! It’s worth the funding since it’ll lead to new cures for the Whathaveyou Syndrome.”

Case in point, I was recently gleaning a few recent cocaine research study news releases and I noticed a distinct lack of reality with the conjecture. All these come from Science Daily which prints articles in their original form from universities and research organizations. This all hyperboles are coming straight from the horses mouth.

“We have a brain hard-wired to appreciate rewards, and cocaine and other drugs of abuse latch onto this system. We are looking at the potential for new medications that reduce the brain’s sensitivity to these conditioned drug cues and would give patients a fighting chance to manage their urges.” (Subconscious Signals Can Trigger Drug Craving) 1

“Based on this study, it appears that promising new therapies for addiction may be based on treatments that mute the desire to escalate cocaine intake by blocking the elevation of brain reward thresholds produced by chronic cocaine use.” (Research Helps Explain Why Perception Of Pleasure Decreases With Chronic Cocaine Use) 2

Anyone with an ounce (28.3495231 grams) of scientific skepticism can see right through any of this, tear into the meat of the study, toss out the wild tangents, and hunt for connections to broader theories and future research ideas. This however is not the journalist’s job. There job is to make the science seem more like SCIENCE!

SCIENCE! journalism — as opposed to science journalism — is useful for keeping science interesting and relevant to the public at large, and hopefully inspiring the next generation of scientists. Of course, it also has it’s problems in that distorts the science, but as I mentioned, scientists are pretty good at doing that themselves.

Footnotes

  1. I.E., put the addict on an antipsychotic (aka dopamine antagonist). Antipsychotics have fun side effects like the desire to sleep a lot, reduced libido, weight gain, and a general anhedonia (they don’t get too exited about anything). Sure it may deaden the cravings (and possibly protect D2 receptors), but will addicts really willingly take a drug that makes them feel like they are in continual withdrawal?
  2. I.E., somehow get the addict to take some sort of anti-psychotic when they are in the middle of their drug binge — even better if it’s their first drug binge. Sorry to burst your bubble but this ain’t gonna happen.
  3. The cocaine vaccine while not a panacea shows some promise — if ethically awkward. I’ve been meaning to write something on it but I want to put a bit more research into that post.

Meow? ~ Cat Lady revisited

Dec 2007 10 – Filed under science

So it seems like my Cat Lady hypothesis linking toxoplasmosis and crazy cattitude that I blogged about in August of 2006 seems to have taken root elsewhere in the scientific community. The New York Times is reporting that the crazy idea may not be so crazy.

“That idea doesn’t seem completely crazy,” Sapolsky says. “But there’s no data supporting it.” [Toxo expert Robert Sapolsky of Stanford]

Not yet. But Jaroslav Flegr, an evolutionary biologist at Charles University in the Czech Republic, is looking into it.

It’s a rather simple leap in logic for anyone who knows the effects of toxoplasmosis, so I’m not surprised that someone else glommed onto the idea. However, I like to think that I may have helped it percolate to the surface, so now it can get some actual scientific study.

The Neuro Cost of War

Mar 2007 19 – Filed under science

I highly recommend watching the fabulous Iraq & Back: Bob Woodruff’s Return (or if you’d rather not watch then read it here). It’s an ABC news documentary about the underreported and troubling number of veterans that are returning with traumatic brain injury. Most fascinating is that the reporter for the story is Bob Woodruff himself who suffered from a massive shrapnel blast to the head from an IED. As a result of his injuries, he was in a coma for 36 days and has had a surprising recovery considering the amount of damage in his left hemisphere.

Officially, the Department of Defense says that 1,835 soldiers and Marines have a traumatic brain injury (TBI), but it is likely that many go undiagnosed. When there is a skull fracture or shrapnel penetration then the damage is plain. However, in this new war of protective armor and IEDs often the helmet does it’s job, but the brain is still slammed around violently. In fact, it is estimated that 10% or more of returning soldiers may have sustained an undiagnosed brain injury — that’s at least 150,000 people.

All this is especially troublesome since there is no routine DoD screening procedure, so veterans who think they may have a problem have to apply for neuropsychological testing themselves. Then even if they know they have a problem, it can often be hard to get rehabilitation treatment.

This is compounded by the problem that the effects of the injury may be subtle. Frontal lobe damage can cause shifts in personality or motivation that may not be noticed readily. This is directly connected to the problem with the DoD neglecting troops’ PTSD and other mental health issues.

If you’re interested in reading more about this, Discover magazine had an article about it last month entitled Dead Men Walking. The Smartbrains blog had a post about TBI earlier this month. Relatedly, Dr. J C writes in brainblogger about how most cases of brain trauma are just watchful waiting with the occasional hole drilling to release pressure. We just don’t know enough to do anything else.

Of course, the elephant in the room with all of this is the potential number of Iraqis facing similar problems with even less access to treatment.